I'm new here and I've only browsed the official site (not much info on systems). To me the multibox question, it depends on how the other systems are. For example If I chose to farm / collect rare items with my time and there's a limited inventory system in place (where it would force me to pick and choose which item to bin/delete/drop), I would want multiboxing so that I can store the items I've worked hard to obtain.
If items/loot are bound to a character / can't be traded then muiltiboxing would not be needed (but in this case, would limit any market / auction house system)